This doesn't qualify as a hot zone, but this is an extremely fun "quest" you can do in Hollowshade Moor. It's called the Hollowshade War. There are 3 factions in the zone, owlbears, grimlings and the sonic wolves. They continually attack each other, never getting anywhere until a player intervenes. Each camp spawns various named mobs with special drops and you can change ownership of the camps by assisting the attacking forces.
The loot used to be very good but is probably useless now. The zone exp modifier probably sucks too, but personally I have never had more fun than running the war here.
I haven't done it in a long time, but these days with mercs you might even be able to attempt this at level 30, 35 as a duo, or perhaps 40 solo.
In my opinion this is one of the most innovative zone ideas done by the EQ team at the time Luclin was released - I'm not sure if it was ever done again. You can change the mobs that populate the entire zone by manipulating this War.
If you want spoilers, look here
Hollowshade War