I know they're pretty cheesy, but the new year can present an opportunity to at least try to focus on changing something about yourself. I've really only got two "resolutions," but have been working on some short- and long-term goals for myself, as I'm not quite happy with where I am in life, and that isn't likely to change on its own.
Lots of people make weight loss a goal, and while I do need to lose weight and have a goal for that, my resolution is just to generally live healthier. The weight loss will come with a healthy lifestyle.
I also want to make an effort to start playing music again. I haven't played much over the past year, and I know my skills have eroded at least somewhat. I should probably find a group to at least jam with occasionally.