The people I know who synth Mithka-bobs for profit, do so because they are high enough to synth Chiefka-bobs. Being a low level cook, I shy away from any Fire crystal synths as much as possible, the cost is just to high.
I hate to break it to you but I farm my own meat and fire crystals so its pretty much a profit for me as long as they don't go too low, that and I do get regular HQ's.