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So in the above scenarios which is the smart route when you want to hand out a potion to your group or guild friend and know it will have impact?
A few examples come to mind. As I said before, Baron Rivendare in Stratholme Undead. In Blackrock Depths, against Lord Incendius (as he is a fire elemental). In Maraudon, definitely nature protection potions against the Princess.
Basically, if you know a boss will be using some kind of magic attack/Area of Effect magic attack, drink a potion. It will cut down on your damage taken, and stop your spell knockbacks.
This would be those times in instances when you are up against a lot of magic-users/elementals. Like... before the Grim Guzzler in BRD, there are groups of three elementals (fire) that can't be pulled separately. You might want a potion at that point.
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2) Elite Mob Quests/Grinding
Against quest mobs, yes. Grinding elites; generally no. Potions can be a good help if you're trying to solo a spell-casting elite mob. That's about all; not feasible against constantly grinded elites; you'll run out of potions quickly.