It depends a lot on your level. I like circling the Badlands - there are lots of mithril nodes in Lethlor Ravine and tucked in the little side valleys among the rock elementals, and lots of iron along all the little mountains in the interior of the zone, as well as a forge for smelting it all down and a vendor for emptying your bags so you can make another trip right in the middle. If that's still a little high, try either the Charred Vale for one or two nodes, or the racetrack area of the Thousand Needles for a couple of nodes. The sea on the northwest side of Desolace also has a number of nodes at the bottom, possibly safer than either of the other two areas if you stay on the surface until you're directly over the node.